Lutte contre les cancers

Menée à Taïwan, cette étude prospective longitudinale analyse les besoins en soins de support de 82 patients nouvellement diagnostiqués avec un cancer de la cavité orale et recevant une radiothérapie

• Supportive care needs in newly diagnosed oral cavity cancer patients receiving radiation therapy
  • Psycho-Oncology, sous presse, 2012 (résumé)
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  Menée à Taïwan, cette étude prospective longitudinale analyse les besoins en soins de support de 82 patients nouvellement diagnostiqués avec un cancer de la cavité orale et recevant une radiothérapie

  “Supportive care needs in newly diagnosed oral cavity cancer patients receiving radiation therapy”

  • Chen, Shu-Ching;Lai, Yeur-Hur;Liao, Chun-Ta;Chang, Joseph Tung-Chien;Lin, Chien-Yu;Fan, Kang-Hsing;Huang, Bing-Shen

  Objective This study aimed to examine changes in physical symptom severity, functional status, supportive care needs, and related factors in oral cavity cancer patients during 6 months after beginning radiation therapy (RT) or concurrent chemotherapy and radiation therapy (CCRT). Methods A prospective longitudinal study was conducted involving oral cavity cancer patients from an RT clinic at a medical center in northern Taiwan. Patients were assessed for supportive care needs and physical symptoms at five time points: before the beginning of RT or CCRT and at 1, 2, 3, and 6 months after beginning RT or CCRT. The generalized estimating equation was used to identify predictors of overall needs as well as six specific dimensions of needs. Results A total of 82 patients completed the 6 months of follow-up. Patients had moderate to high levels of supportive care needs over the 6 months. Although the highest information need was at the pretreatment phase, in general, the peak for ...

  
  

Mots clés : Voies aérodigestives supérieures; Lutte contre les cancers (Qualité de vie, soins de support)

Menée aux Pays-Bas par questionnaire en ligne, cette étude analyse la prévalence des dysfonctionnements et troubles sexuels chez des femmes jeunes (âgées de moins de 45 ans) et atteintes d'un cancer du sein

• Sexual dysfunction in young women with breast cancer
  • Supportive Care in Cancer, sous presse, 2012 (résumé)
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  Menée aux Pays-Bas par questionnaire en ligne, cette étude analyse la prévalence des dysfonctionnements et troubles sexuels chez des femmes jeunes (âgées de moins de 45 ans) et atteintes d'un cancer du sein

  “Sexual dysfunction in young women with breast cancer”

  • Kedde, H.;van de Wiel, H.;Weijmar Schultz, W.;Wijsen, C.

  Objectives The objective of this study was to determine the prevalence of sexual dysfunction in young women with breast cancer in the Netherlands, and to assess the relationship between sexual dysfunction, treatment methods and treatment-related complaints. Also, the interest among women with breast cancer in receiving care for sexual dysfunction was determined. Methods Data on sexual functioning were collected through an internet questionnaire. Respondents were included if they had been diagnosed with breast cancer within the past 6 years and were currently 45 years of age or younger. Results were compared with a representative sample of the general Dutch population Results Of the women who were still undergoing treatment, 64 % had a sexual dysfunction. In women who had completed treatment, this was 45 %. All assessed dysfunctions were more common among these young women with breast cancer in comparison with women in the Dutch population. Particularly, early menopause and hormone ...

  
  

Mots clés : Sein; Lutte contre les cancers (Qualité de vie, soins de support)

Menée à Hong Kong auprès de patientes chinoises atteintes d'un cancer du sein de stade avancé, cette étude analyse leurs besoins en soins de support

• Supportive care needs in Hong Kong Chinese women confronting advanced breast cancer
  • Psycho-Oncology, sous presse, 2012 (résumé)
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  Menée à Hong Kong auprès de patientes chinoises atteintes d'un cancer du sein de stade avancé, cette étude analyse leurs besoins en soins de support

  “Supportive care needs in Hong Kong Chinese women confronting advanced breast cancer”

  • Au, Angel;Lam, Wendy;Tsang, Janice;Yau, Tsz-kok;Soong, Inda;Yeo, Winnie;Suen, Joyce;Ho, Wing M.;Wong, Ka-yan;Kwong, Ava;Suen, Dacita;Sze, Wing-Kin;Ng, Alice;Girgis, Afaf;Fielding, Richard

  Background Women with advanced breast cancer (ABC) are living longer, so understanding their needs becomes important. This cross-sectional study investigated the type and extent of unmet supportive care needs in Hong Kong Chinese women with advanced breast cancer. Methods Face-to-face interviews were conducted among women with stage III or stage IV disease mostly awaiting chemotherapy (76%) to identify unmet needs using the Supportive Care Needs Survey Short Form, psychological morbidity using the Hospital Anxiety and Depression Scale, symptom distress using the Memorial Symptom Assessment Scale, and satisfaction with care using the Patient satisfaction questionnaire (PSQ-9). Results About 27–72% of 198/220 (90%) women (mean age = 53.4 ± 9.74 (standard deviation) years) identified needs from the health system, information, and patient support (HSIPS) domain as the top 15 most prevalent unmet needs. ‘having one member of hospital staff with whom you can talk to about all ...

  
  

Mots clés : Sein; Lutte contre les cancers (Qualité de vie, soins de support)

Menée au Canada, cette étude analyse l'évolution de l'incidence du cancer de l'oropharynx et des cancers de la tête et du cou associés à une infection par le papillomavirus humain, sur la période 1992-2009

• Incidence trends in head and neck cancers and human papillomavirus (HPV)-associated oropharyngeal cancer in Canada, 1992–2009
  • Cancer Causes and Control, sous presse, 2012 (résumé)
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  Menée au Canada, cette étude analyse l'évolution de l'incidence du cancer de l'oropharynx et des cancers de la tête et du cou associés à une infection par le papillomavirus humain, sur la période 1992-2009

  “Incidence trends in head and neck cancers and human papillomavirus (HPV)-associated oropharyngeal cancer in Canada, 1992–2009”

  • Forte, Tonia;Niu, Jin;Lockwood, Gina;Bryant, Heather

  Purpose Recently, human papillomavirus (HPV) infection has been causally associated with a subset of head and neck cancers, particularly oropharyngeal cancer. As national cancer reporting systems typically report incidence rates of oropharyngeal cancer grouped with other cancers of the head and neck region, the objective of this study was to present age-standardized incidence trends in oropharyngeal cancer Canada-wide. Methods Data were obtained from the Canadian Cancer Registry for cases diagnosed between 1992 and 2009. Trends in age-standardized incidence rates were described for head and neck cancers overall and for HPV-associated oropharyngeal cancer using Joinpoint regression. Results The age-standardized incidence of head and neck cancers declined significantly in Canada from 1992 to 1998 (annual percentage change [APC] = −3.0, p < 0.01), then remained stable through to 2009. In contrast, the age-standardized incidence of HPV-associated oropharyngeal cancer increased ...

  
  

Mots clés : Voies aérodigestives supérieures; Lutte contre les cancers (Observation)

Cette étude multicentrique identifie les facteurs associés à l'utilisation d'une radiochirurgie stéréotaxique pour traiter des métastases cérébrales après une radiothérapie du cerveau entier (898 cas)

• A Multi-institutional Study of Factors Influencing the Use of Stereotactic Radiosurgery for Brain Metastases
  • International journal of radiation oncology, biology, physics, sous presse, 2012 (résumé)
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  Cette étude multicentrique identifie les facteurs associés à l'utilisation d'une radiochirurgie stéréotaxique pour traiter des métastases cérébrales après une radiothérapie du cerveau entier (898 cas)

  “A Multi-institutional Study of Factors Influencing the Use of Stereotactic Radiosurgery for Brain Metastases”

  • Hodgson, David C.;Charpentier, Anne-Marie;Cigsar, Candemir;Atenafu, Eshetu G.;Ng, Angela;Bahl, Guarav;Zadeh, Gelareh;Miguel, John San;Menard, Cynthia

  Stereotactic radiosurgery (SRS) for brain metastases is a relatively well-studied technology with established guidelines regarding patient selection, although its implementation is technically complex. We evaluated the extent to which local availability of SRS affected the treatment of patients with brain metastases. We identified 3030 patients who received whole-brain radiation therapy (WBRT) for brain metastases in 1 of 7 cancer centers in Ontario. Clinical data were abstracted for a random sample of 973 patients. Logistic regression analyses were performed to identify factors associated with the use of SRS as a boost within 4 months following WBRT or at any time following WBRT. Of 898 patients eligible for analysis, SRS was provided to 70 (7.8%) patients at some time during the course of their disease and to 34 (3.8%) patients as a boost following WBRT. In multivariable analyses, factors significantly associated with the use of SRS boost following WBRT were fewer brain metastases ...

  
  

Mots clés : Système nerveux central; Lutte contre les cancers (Observation)

Menée sur 864 patients atteints d'un carcinome urothélial des voies excrétrices supérieures et traités par néphro-urétérectomie radicale (durée médiane de suivi : 50 mois), cette étude multicentrique évalue le stade tumoral, la mortalité spécifique et le taux de récidive en fonction du statut tabagique des patients

• Impact of Smoking on Oncologic Outcomes of Upper Tract Urothelial Carcinoma After Radical Nephroureterectomy
  • European urology, sous presse, 2012 (résumé)
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  Menée sur 864 patients atteints d'un carcinome urothélial des voies excrétrices supérieures et traités par néphro-urétérectomie radicale (durée médiane de suivi : 50 mois), cette étude multicentrique évalue le stade tumoral, la mortalité spécifique et le taux de récidive en fonction du statut tabagique des patients

  “Impact of Smoking on Oncologic Outcomes of Upper Tract Urothelial Carcinoma After Radical Nephroureterectomy”

  • Michael, Rink;Evanguelos, Xylinas;Vitaly, Margulis;Eugene, K. Cha;Behfar, Ehdaie;Jay, D. Raman;Felix, K. Chun;Kazumasa, Matsumoto;Yair, Lotan;Helena, Furberg;Marek, Babjuk;Armin, Pycha;Christopher, G. Wood;Pierre, I. Karakiewicz;Margit, Fisch;Douglas, S. Scherr;Shahrokh, F. Shariat;for the Upper Tract Urothelial Carcinoma Collaboration, n

  Background : Cigarette smoking is a common risk factor for developing upper tract urothelial carcinoma (UTUC). Objective :To assess the impact of cigarette smoking status, cumulative smoking exposure, and time from cessation on oncologic UTUC outcomes in patients treated with radical nephroureterectomy (RNU). Design, setting, and participants : A total of 864 patients underwent RNU at five institutions. The median follow-up in this retrospective study was 50 mo. Smoking history included smoking status, quantity of cigarettes per day (CPD), duration in years, and years from smoking cessation. The cumulative smoking exposure was categorized as light-short-term (≤19 CPD and ≤19.9 yr), moderate (all combinations except light-short-term and heavy-long-term), and heavy-long-term (≥20 CPD and ≥20 yr). Interventions : RNU with or without lymph node dissection. No patient received neoadjuvant chemotherapy. Outcome measurements and statistical analysis : Univariable and multivariable ...

  
  

Mots clés : Rein; Lutte contre les cancers (Observation)

Menée en population néerlandaise, cette étude analyse l'évolution de l'incidence du mélanome, l'épaisseur du mélanome mesuré avec l'indice de Breslow, et la survie des patients, en fonction de l'âge (plus ou moins de 65 ans) sur la période 1994-2008

• Breslow thickness in the Netherlands: a population-based study of 40 880 patients comparing young and elderly patients
  • British Journal of Cancer, sous presse, 2012 (résumé)
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  Menée en population néerlandaise, cette étude analyse l'évolution de l'incidence du mélanome, l'épaisseur du mélanome mesuré avec l'indice de Breslow, et la survie des patients, en fonction de l'âge (plus ou moins de 65 ans) sur la période 1994-2008

  “Breslow thickness in the Netherlands: a population-based study of 40 880 patients comparing young and elderly patients”

  • Kruijff, S.;Bastiaannet, E.;Francken, A. B.;Schaapveld, M.;van der Aa, M.;Hoekstra, H. J.

  Melanoma incidence has increased rapidly in the last decades, and predictions show a continuing increase in the years to come. The aim of this study was to assess trends in melanoma incidence, Breslow thickness (BT), and melanoma survival among young and elderly patients in the Netherlands. Methods: Patients diagnosed with invasive melanoma between 1994 and 2008 were selected from the Netherlands Cancer Registry. Incidence (per 100 000) over time was calculated for young (<65 years) and elderly patients (65 years). Distribution of BT for young and elderly males and females was assessed. Regression analysis of the log-transformed BT was used to assess changes over time. Relative survival was calculated as the ratio of observed survival to expected survival. Results: Overall, 40 880 patients were included (42.3% male and 57.7% female). Melanoma incidence increased more rapidly among the elderly (5.4% estimated annual percentage change (EAPC), P<0.0001) than among younger patients ...

  
  

Mots clés : Mélanome; Lutte contre les cancers (Observation)

Menée au Royaume-Uni à partir des données de trois cohortes suivies pendant 10 ans (1973–1982, 1983–1992 and 1993–2002), cette étude analyse l'évolution de la survie à long terme de patients ayant été traités pour un lymphome hodgkinien

• Long-term survival after treatment for Hodgkin/'s disease (1973-2002): improved survival with successive 10-year cohorts
  • British Journal of Cancer, sous presse, 2012 (résumé)
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  Menée au Royaume-Uni à partir des données de trois cohortes suivies pendant 10 ans (1973–1982, 1983–1992 and 1993–2002), cette étude analyse l'évolution de la survie à long terme de patients ayant été traités pour un lymphome hodgkinien

  “Long-term survival after treatment for Hodgkin/'s disease (1973-2002): improved survival with successive 10-year cohorts”

  • Bessell, E. M.;Bouliotis, G.;Armstrong, S.;Baddeley, J.;Haynes, A. P.;O'Connor, S.;Nicholls-Elliott, H.;Bradley, M.

  Background: The Nottinghamshire Lymphoma Registry contains the details of all the patients diagnosed with lymphoma (since 1 January 1973) within a defined geographical area with a population of 1.1 million. It was therefore possible to study the outcome of treatment for Hodgkin’s disease for three 10-year cohorts (1973–1982, 1983–1992 and 1993–2002). The aims of the study were to compare survival time among the three patient cohorts, to identify prognostic factors and to estimate relative survival. Methods: A total of 745 patients diagnosed between 1973 and 2002 were analysed for survival. Survivorship was estimated by the Kaplan-Meier method and parametric survival models. An accelerated failure-time regression was used for multivariate analysis. Results: Overall, patients were observed for 9.8 (0.3–34.82) years (median(range)), on average. One, five and fifteen-year disease-specific survival was found to be 87% (85–90%), 77% (74–80%) and 70% (67–74%), respectively. ...

  
  

Mots clés : Lymphome; Lutte contre les cancers (Observation)

Menée en Norvège, cette étude de cohorte rétrospective (2 008 cas et 3 240 témoins) analyse la prévalence des arrêts-maladie de survivants de cancer, sur une durée de cinq ans après le diagnostic, en fonction de critères socio-démographiques et de facteurs cliniques

• Sick leave patterns among 5-year cancer survivors: a registry-based retrospective cohort study
  • Journal of Cancer Survivorship, sous presse, 2012 (résumé)
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  Menée en Norvège, cette étude de cohorte rétrospective (2 008 cas et 3 240 témoins) analyse la prévalence des arrêts-maladie de survivants de cancer, sur une durée de cinq ans après le diagnostic, en fonction de critères socio-démographiques et de facteurs cliniques

  “Sick leave patterns among 5-year cancer survivors: a registry-based retrospective cohort study”

  • Torp, Steffen;Nielsen, Roy;Gudbergsson, Sævar;Fosså, Sophie;Dahl, Alv

  Purpose The aims of this study were to observe the sick leave rates of cancer survivors for five consecutive years following a first lifetime diagnosis of invasive cancer and to identify socio-demographic and clinical predictors of sick leave taken in the fifth year after diagnosis. Methods This registry study comprised 2,008 Norwegian individuals (18–61 years old) with their first lifetime diagnosis of invasive cancer in 1999 and alive in 2004 and a cancer-free control group ( n = 3,240) matched by sex, age, educational level, and employment status in 1998. Sick leave was defined as at least one sick leave period >16 days within the year in question. Results A total of 75 % of the long-term cancer survivors (LTCSs) took sick leave within the first 12 months after their diagnosis. The sick leave rate stabilized at a slightly higher level in the following 4 years compared to the year before diagnosis, with approximately 23 % of the male and 31 % of the female LTCSs taking sick ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Observation)

Menée aux Etats-Unis sur la période 2006 à 2008, cette étude analyse et compare, pour les femmes d'origine hispanique et amérindienne, le recours aux dépistages du cancer du sein et du cancer du col de l'utérus, selon qu'elles vivent en zone rurale ou en zone urbaine

• Comparison of breast and cervical cancer screening utilization among rural and urban Hispanic and American Indian women in the Southwestern United States
  • Cancer Causes and Control, sous presse, 2012 (résumé)
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  Menée aux Etats-Unis sur la période 2006 à 2008, cette étude analyse et compare, pour les femmes d'origine hispanique et amérindienne, le recours aux dépistages du cancer du sein et du cancer du col de l'utérus, selon qu'elles vivent en zone rurale ou en zone urbaine

  “Comparison of breast and cervical cancer screening utilization among rural and urban Hispanic and American Indian women in the Southwestern United States”

  • Nuño, Tomas;Gerald, Joe;Harris, Robin;Martinez, Maria;Estrada, Antonio;García, Francisco

  Objective Rural Hispanic and American Indian (AI) women are at risk of non-participation in cancer screening programs. The objective of this study was to compare breast and cervical cancer screening utilization among Hispanic and AI women that reside in rural areas of the Southwestern United States to their urban counterparts and to assess characteristics that influence cancer screening. Methods This study utilizes Behavioral Risk Factor Surveillance System (BRFSS) data from 2006 to 2008 for Arizona and New Mexico. The BRFSS is a federally funded telephone survey to collect data on risk factors contributing to the leading causes of death and chronic diseases. Results Rural Hispanic and AI populations reported some differences in screening rates compared with their urban counterparts. Among Hispanic women, 58 % of rural residents reported having had a mammogram within the past year, compared with 66 % of urban residents. Among AI women, 81 % of rural residents had ever had a mammogram, ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Observation)

A partir des données du registe suédois du cancer portant sur la période 1987-2008, cette étude analyse les sites spécifiques en cause dans la mort de patients atteints d'un cancer d'origine primitive inconnue mais ayant été diagnostiqués avec des métastases des ganglions lymphatiques

• Site-specific cancer deaths in cancer of unknown primary diagnosed with lymph node metastasis may reveal hidden primaries
  • International Journal of Cancer, sous presse, 2012 (résumé)
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  A partir des données du registe suédois du cancer portant sur la période 1987-2008, cette étude analyse les sites spécifiques en cause dans la mort de patients atteints d'un cancer d'origine primitive inconnue mais ayant été diagnostiqués avec des métastases des ganglions lymphatiques

  “Site-specific cancer deaths in cancer of unknown primary diagnosed with lymph node metastasis may reveal hidden primaries”

  • Hemminki, K.;Bevier, M.;Sundquist, J.;Hemminki, A.

  Cancer of unknown primary site (CUP) is a fatal cancer ranking among the five most common cancer deaths. CUP is diagnosed through metastases, which are limited to lymph nodes in some patients. Cause-specific survival data could guide the search for hidden primary tumors and help with therapeutic choices. The CUP patients were identified from the Swedish Cancer Registry between 1987 and 2008; 1444 patients had only lymph node metastasis of defined histology (adenocarcinoma, squamous cell or undifferentiated). Site-specific cancer deaths were analyzed by lymph node location and histology. Kaplan-Meier survival curves were compared with metastatic primary cancer at related sites. Among the patients with metastasis to head and neck lymph nodes, 117 (59.1% of the specific cancer deaths) died of lung tumors. Patients with axillary lymph node metastasis died of lung and breast tumors in equal proportions (40.2% each). Also, squamous cell CUP in head and neck lymph nodes was mainly associated ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Observation)

A partir d'une revue systématique de la littérature publiée entre 1947 et 2011 (6 essais randomisés contrôlés), cette étude fait le point sur les diverses interventions de nature psychosociale destinées à améliorer la qualité de vie de soignants de patients atteints d'un cancer

• A systematic review of psychosocial interventions to improve cancer caregiver quality of life
  • Psycho-Oncology, sous presse, 2012 (résumé)
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  A partir d'une revue systématique de la littérature publiée entre 1947 et 2011 (6 essais randomisés contrôlés), cette étude fait le point sur les diverses interventions de nature psychosociale destinées à améliorer la qualité de vie de soignants de patients atteints d'un cancer

  “A systematic review of psychosocial interventions to improve cancer caregiver quality of life”

  • Waldron, Elizabeth A.;Janke, E. Amy;Bechtel, Colleen F.;Ramirez, Michelle;Cohen, Abigail

  Objective To evaluate and estimate the effect of psychosocial interventions on improving the quality of life (QoL) of adult cancer caregivers. Methods We conducted a systematic review of randomized controlled trials among adult cancer caregivers published from 1947 to 2011. Rigorous inclusion criteria included randomization of caregivers, use of control groups, and at least one active psychosocial intervention where caregiver QoL was measured. A pair of raters independently reviewed all abstracts, and studies were assessed for quality using an 11-item PEDro coding scale. Data were extracted, examined, and synthesized using a narrative approach. Results Six randomized controlled trials met inclusion criteria out of 1066 identified abstracts. Studies were rejected because of methodological flaws and failure to report a measure of caregiver QoL. A total of 1115 caregivers were included at baseline measurements. Estimated effect sizes for included studies were nil to small ranging from ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Approches psycho-sociales)

Menée en Australie auprès de 505 participants, cette étude analyse les diverses perceptions de patients atteints d'un cancer de stade avancé face aux notions de survie et d'espérance de vie

• Using scenarios to explain life expectancy in advanced cancer: attitudes of people with a cancer experience
  • Supportive Care in Cancer, sous presse, 2012 (résumé)
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  Menée en Australie auprès de 505 participants, cette étude analyse les diverses perceptions de patients atteints d'un cancer de stade avancé face aux notions de survie et d'espérance de vie

  “Using scenarios to explain life expectancy in advanced cancer: attitudes of people with a cancer experience”

  • Kiely, B.;McCaughan, G.;Christodoulou, S.;Beale, P.;Grimison, P.;Trotman, J.;Tattersall, M.;Stockler, M.

  Purpose We sought the attitudes of people with a cancer experience to using best case, worst case, and typical scenarios for survival to explain life expectancy. Methods Oncology clinic attendees and Breast Cancer Network Australia (BCNA) members completed a survey describing two formats for explaining life expectancy to a hypothetical patient with advanced cancer—providing either three scenarios for survival or just the median survival time. Results Characteristics of the 505 respondents from outpatient clinics ( n = 251) and BCNA ( n = 254) were median age of 58 years, female 74 %, and breast primary 64 %. More respondents agreed that explaining three scenarios (vs. median survival) would make sense (93 vs. 75 %), be helpful (93 vs. 69 %), convey hope (68 vs. 44 %), and reassure (60 vs. 40 %), while fewer respondents agreed that explaining three scenarios (vs. median survival) would upset people (24 vs. 36 %); all p values < 0.001. Most respondents agreed that each scenario ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Approches psycho-sociales)

Menée aux Etats-Unis auprès de 148 participants, cette étude transversale analyse les différentes façons de faire face à la maladie et le stress de soignants et aidants familiaux d'un patient atteint de cancer

• Coping and its effects on cancer caregiving
  • Supportive Care in Cancer, sous presse, 2012 (résumé)
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  Menée aux Etats-Unis auprès de 148 participants, cette étude transversale analyse les différentes façons de faire face à la maladie et le stress de soignants et aidants familiaux d'un patient atteint de cancer

  “Coping and its effects on cancer caregiving”

  • Gaugler, Joseph;Eppinger, Alejandra;King, Jamie;Sandberg, Tracey;Regine, William

  Purpose Various studies have documented the emotional distress family members of persons with cancer experience, and descriptive research has identified those psychosocial factors that protect cancer caregivers from a range of negative outcomes. The objective of this study was to determine how different coping strategies were associated with multiple domains of stress and negative health outcomes among cancer family caregivers. Methods A cross-sectional, correlational study design was used. One hundred forty-eight family caregivers of persons with cancer from the University of Minnesota Masonic Cancer Center and the University of Maryland Greenebaum Cancer Center were included. Results Multiple regression models found that negative expectation coping strategies (worrying, expecting the worst, and getting nervous) and cancer caregivers’ perceptions of not coping well were most significantly associated with emotional distress and negative psychological outcomes. Conclusion Coping ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Approches psycho-sociales)

Menée en Italie, cette étude de cohorte rétrospective analyse le phénomène des visites répétées imprévues et des demandes d'admission hospitalière par des patients atteints de cancer et suivis à l'extérieur de l'hôpital

• Unplanned presentations of cancer outpatients: a retrospective cohort study
  • Supportive Care in Cancer, sous presse, 2012 (résumé)
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  Menée en Italie, cette étude de cohorte rétrospective analyse le phénomène des visites répétées imprévues et des demandes d'admission hospitalière par des patients atteints de cancer et suivis à l'extérieur de l'hôpital

  “Unplanned presentations of cancer outpatients: a retrospective cohort study”

  • Aprile, G.;Pisa, F.;Follador, A.;Foltran, L.;De Pauli, F.;Mazzer, M.;Lutrino, S.;Sacco, C.;Mansutti, M.;Fasola, G.

  Purpose As a result of the growing cancer incidence and the increasing trend towards chemotherapy treatment, a higher number of cancer outpatients ask for unplanned visits. This study aimed to describe the nature and magnitude of this phenomenon and to identify risk factors for repeated unplanned presentations and hospital admission. Methods Unplanned consultations (2,811) of 1,431 cancer patients who accessed our acute oncology clinic over a 2-year period were reviewed. Demographics, clinical variables and reason(s) for presentation were all recorded. Recurrent event survival analysis was used to evaluate the relation of potential predictors to the two outcome events repeated presentations and hospitalization. A stratified Cox proportional hazard model was used. Results Of 1,431 patients, 625 (43 %) received chemotherapy during the 90 days before the unplanned visit. Pain (27.7 %), fatigue (17.6 %), dyspnoea (13.8 %), fever (11.5 %) and gastrointestinal problems (31 %) were reported ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Analyses économiques et systèmes de soins)

Menée auprès de 146 participants recevant des soins palliatifs, cette étude rétrospective évalue l'association entre une pneumonie et la survenue d'un délire chez des patients atteints d'un cancer du poumon en phase terminale

• Impact of pneumonia on hyperactive delirium in end-stage lung cancer patients
  • Supportive Care in Cancer, sous presse, 2012 (résumé)
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  Menée auprès de 146 participants recevant des soins palliatifs, cette étude rétrospective évalue l'association entre une pneumonie et la survenue d'un délire chez des patients atteints d'un cancer du poumon en phase terminale

  “Impact of pneumonia on hyperactive delirium in end-stage lung cancer patients”

  • Suzuki, Hidekazu;Hirashima, Tomonori;Kobayashi, Masashi;Okamoto, Norio;Matsuura, Yuka;Tamiya, Motohiro;Morishita, Naoko;Okafuji, Kohei;Shiroyama, Takayuki;Morimura, Osamu;Morita, Satomu;Kawase, Ichiro

  Purpose Patients with incurable lung cancer often receive palliative care. Hyperactive delirium is a burden not only for the patient’s family but also for caregivers. There are no reports describing the risk factors for delirium among lung cancer patients. The present study investigated the frequency of incidence and risk factors for hyperactive delirium among end-stage lung cancer patients. Methods Patients who died of lung cancer in our institute from January 2010 to December 2010 were retrospectively investigated. Information was obtained from medical records, and patients who developed hyperactive delirium (delirium group, group D) were compared with patients who did not (control group, group C) based on clinical and laboratory data. Results A total of 146 patients (median age, 70 years; 80 % male) died of lung cancer. Thirty-one (21.2 %) patients developed hyperactive delirium. Sex ( P = 0.0093) and pneumonia ( P = 0.023) were statistically significant variables in univariate ...

  
  

Mots clés : Poumon; Lutte contre les cancers (Soins palliatifs)

Cette étude présente et propose un algorithme de lissage spatial pour identifier et définir une zone géographique à taux élevé de mortalité par cancer du poumon aux Etats-Unis

• Implementing a weighted spatial smoothing algorithm to identify a lung cancer belt in the United States
  • Cancer Epidemiology, sous presse, 2012 (résumé)
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  Cette étude présente et propose un algorithme de lissage spatial pour identifier et définir une zone géographique à taux élevé de mortalité par cancer du poumon aux Etats-Unis

  “Implementing a weighted spatial smoothing algorithm to identify a lung cancer belt in the United States”

  • Blackley, David;Zheng, Shimin;Ketchum, Winn

  Lung cancer is the leading cause of cancer death in the United States, but a large fraction of cases is preventable. We use a spatial smoothing algorithm to identify a geographic pattern of high lung cancer mortality, primarily in the Southeast, which we call a lung cancer belt. Disease belts are an effective mode for conveying patterns of high incidence or mortality; formally defining this lung cancer belt may encourage increased public dialogue and more focused research. Public health officials could complement existing population lung cancer data with this information to help inform resource allocation decisions.

  
  

Mots clés : Poumon; Lutte contre les cancers (Ressources et infrastructures (Lutte contre les cancers))

Menée en Angleterre, cette étude de cohorte en population analyse l'exactitude des données relatives au diagnostic de cancers dans une base de données des pratiques de médecine générale en les comparant aux données des registres des cancers

• Validity of cancer diagnosis in a primary care database compared with linked cancer registrations in England. Population-based cohort study
  • Cancer Epidemiology, sous presse, 2012 (résumé)
  Détails

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  Menée en Angleterre, cette étude de cohorte en population analyse l'exactitude des données relatives au diagnostic de cancers dans une base de données des pratiques de médecine générale en les comparant aux données des registres des cancers

  “Validity of cancer diagnosis in a primary care database compared with linked cancer registrations in England. Population-based cohort study”

  • Dregan, A.;Moller, H.;Murray-Thomas, T.;Gulliford, M. C.

  Aims The present study aimed to evaluate the validity of cancer diagnoses and death recording in a primary care database compared with cancer registry (CR) data in England. Methods The eligible cohort comprised 42,556 participants, registered with English general practices in the General Practice Research Database (GPRD) that consented to CR linkage. CR and primary care records were compared for cancer diagnosis, date of cancer diagnosis and death. Read and ICD cancer code sets were reviewed and agreed by two authors. Results There were 5216 (91% of CR total) cancer events diagnosed in both sources. There were 494 (9%) diagnosed in CR only and 213 (4%) that were diagnosed in GPRD only. The predictive value of a GPRD cancer diagnosis was 96% for lung cancer, 92% for urinary tract cancer, 96% for gastro-oesophageal cancer and 98% for colorectal cancer. ‘False negative’ primary care records were sometimes accounted for by registration end dates being shortly before cancer diagnosis ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Ressources et infrastructures (Lutte contre les cancers))

Menée au Royaume-Uni auprès de 15 patients atteints de cancer et de 15 médecins, cette étude analyse leurs points de vue et préférences relatifs au meilleur moment pour les inclure dans des recherches longitudinales portant sur la survie après un diagnostic de cancer

• Cancer patients’ and clinicians’ opinions on the best time in secondary care to approach patients for recruitment to longitudinal questionnaire-based research
  • Supportive Care in Cancer, sous presse, 2012 (résumé)
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  Menée au Royaume-Uni auprès de 15 patients atteints de cancer et de 15 médecins, cette étude analyse leurs points de vue et préférences relatifs au meilleur moment pour les inclure dans des recherches longitudinales portant sur la survie après un diagnostic de cancer

  “Cancer patients’ and clinicians’ opinions on the best time in secondary care to approach patients for recruitment to longitudinal questionnaire-based research”

  • Ashley, Laura;Jones, Helen;Velikova, Galina;Wright, Penny

  Purpose A priority of the UK National Cancer Survivorship Initiative is to increase collection of patient-reported outcome measures (PROMs) longitudinally post-diagnosis. This study aimed to gather cancer patients’ and clinicians’ opinions and preferences about the best time, in the secondary care pathway, to approach patients about joining longitudinal observational PROMs-based (LO-PROMs) research. Methods The sample comprised 15 patients with non-metastatic breast, colorectal or prostate cancer, and 15 clinicians including surgeons, oncologists and nurse specialists. Patients and clinicians participated in one face-to-face topic-guided audio-recorded interview. Data were analysed using thematic content analysis. Results Patients did not want to be approached about LO-PROMs research early in the care pathway, near diagnosis and treatment planning or before any surgery and its results. Patients felt that LO-PROMs research is best introduced from the time people are ‘settled’ ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Ressources et infrastructures (Lutte contre les cancers))