Lutte contre les cancers

Menée au Canada auprès de 176 survivantes d'un cancer du sein, cette étude analyse leurs capacités psychologiques d'adaptation, leur activité physique, leur bien-être et leur santé mentale et physique

• Goal adjustment, physical and sedentary activity, and well-being and health among breast cancer survivors
  • Psycho-Oncology, sous presse, 2012 (résumé)
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  Menée au Canada auprès de 176 survivantes d'un cancer du sein, cette étude analyse leurs capacités psychologiques d'adaptation, leur activité physique, leur bien-être et leur santé mentale et physique

  “Goal adjustment, physical and sedentary activity, and well-being and health among breast cancer survivors”

  • Wrosch, Carsten;Sabiston, Catherine M.

  Objective This longitudinal study examined whether goal adjustment capacities (i.e., goal disengagement and goal reengagement) would predict breast cancer survivors' emotional well-being and physical health by facilitating high levels of physical activity and low levels of sedentary activity. Methods Self-reports of goal adjustment capacities were measured among 176 female breast cancer survivors at baseline. Self-reports of physical activity, sedentary activity, daily affect, and daily physical health symptoms (e.g., nausea or pain) were measured at baseline and 3-month follow-up. Results Goal reengagement predicted high levels of positive affect and low levels of physical symptoms at baseline and increases in positive affect over 3 months. The combination of high goal disengagement and high goal reengagement was associated with particularly large 3-month increases in positive affect. The effects of goal reengagement on baseline affect and physical health were mediated by high ...

  
  

Mots clés : Sein; Lutte contre les cancers (Qualité de vie, soins de support)

Menée auprès de femmes afro-américaines atteintes d'un cancer du sein, cette étude pilote analyse leurs connaissances relatives à l'impact des traitements sur leur fertilité et conclut à la nécessité de développer l'information sur ce sujet

• A pilot study to examine patient awareness and provider discussion of the impact of cancer treatment on fertility in a registry-based sample of African American women with breast cancer
  • Supportive Care in Cancer, pp. 1-6, 2012 (résumé)
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  Menée auprès de femmes afro-américaines atteintes d'un cancer du sein, cette étude pilote analyse leurs connaissances relatives à l'impact des traitements sur leur fertilité et conclut à la nécessité de développer l'information sur ce sujet

  “A pilot study to examine patient awareness and provider discussion of the impact of cancer treatment on fertility in a registry-based sample of African American women with breast cancer”

  • Vadaparampil, Susan;Christie, Juliette;Quinn, Gwendolyn;Fleming, Patrice;Stowe, Caitlin;Bower, Bethanne;Pal, Tuya

  Purpose Fertility is a concern for many cancer patients diagnosed during their reproductive years. Although African American women are more likely to be diagnosed with early breast cancer (i.e., ≤age 40), little is known about patient awareness of or provider discussion related to fertility in this group. We examined African American women's awareness of the possible impact of cancer treatment on fertility. Methods In a cross-sectional survey of African American women with early-onset breast cancer, demographic and clinical variables were compared with patient awareness and physician discussion of potential fertility loss. Results For women in our sample ( N = 48), 45.8% reported being aware of the potential impact of cancer treatment on fertility, and 56.3% reported that their providers discussed fertility with them. Bivariate analyses demonstrated that awareness was significantly higher in women diagnosed at age ≤45 ( p < 0.05), who were nulliparous ( p < 0.01), or who did ...

  
  

Mots clés : Sein; Lutte contre les cancers (Qualité de vie, soins de support)

Menée par questionnaire auprès de 357 patients atteints d'un cancer de la prostate et 357 témoins, cette étude analyse leurs choix thérapeutiques en fonction des conséquences à long terme des différentes alternatives proposées

• Survival gains needed to offset persistent adverse treatment effects in localised prostate cancer
  • British Journal of Cancer, sous presse, 2012 (résumé)
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  Menée par questionnaire auprès de 357 patients atteints d'un cancer de la prostate et 357 témoins, cette étude analyse leurs choix thérapeutiques en fonction des conséquences à long terme des différentes alternatives proposées

  “Survival gains needed to offset persistent adverse treatment effects in localised prostate cancer”

  • King, M. T.;Viney, R.;Smith, D. P.;Hossain, I.;Street, D.;Savage, E.;Fowler, S.;Berry, M. P.;Stockler, M.;Cozzi, P.;Stricker, P.;Ward, J.;Armstrong, B. K.

  Men diagnosed with localised prostate cancer (LPC) face difficult choices between treatment options that can cause persistent problems with sexual, urinary and bowel function. Controlled trial evidence about the survival benefits of the full range of treatment alternatives is limited, and patients’ views on the survival gains that might justify these problems have not been quantified. Methods: A discrete choice experiment (DCE) was administered in a random subsample (n=357, stratified by treatment) of a population-based sample (n=1381) of men, recurrence-free 3 years after diagnosis of LPC, and 65 age-matched controls (without prostate cancer). Survival gains needed to justify persistent problems were estimated by substituting side effect and survival parameters from the DCE into an equation for compensating variation (adapted from welfare economics). Results: Median (2.5, 97.5 centiles) survival benefits needed to justify severe erectile dysfunction and severe loss of libido were ...

  
  

Mots clés : Prostate; Lutte contre les cancers (Qualité de vie, soins de support)

Menée en Italie auprès de 123 patients atteints de cancer, cette étude analyse l'impact des effets indésirables des traitements sur leur qualité de vie, notamment psychique

• Treatment-related side effects and quality of life in cancer patients
  • Supportive Care in Cancer, pp. 1-5, 2012 (résumé)
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  Menée en Italie auprès de 123 patients atteints de cancer, cette étude analyse l'impact des effets indésirables des traitements sur leur qualité de vie, notamment psychique

  “Treatment-related side effects and quality of life in cancer patients”

  • Mazzotti, Eva;Antonini Cappellini, Gian;Buconovo, Stefania;Morese, Roberto;Scoppola, Alessandro;Sebastiani, Claudia;Marchetti, Paolo

  Background Cancer leads to a complicated pattern of change in quality of life (QoL). Objective The aims of this study were to assess the impact of treatment-related side effects on QoL in cancer patients and to explore which other factors, and to what extent, contribute to explain low QoL scores. Methods One hundred twenty-three cancer patients receiving chemotherapy completed the self-administered questionnaires (Medical Outcomes Short-Form-36 (SF-36) and 12-item General Health Questionnaire). Multiple regression analyses were conducted with the SF-36 physical component summary (PCS) and SF-36 mental component summary (MCS) scores as the dependent variables and demographic and clinical factors as independent variables. Results Seventy-two percent of patients experienced treatment-related side effects, and 32% resulted positive for psychiatric diseases. Two multivariate analyses showed that worse PCS scores, like worse MCS scores, were significantly and independently predicted by ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Qualité de vie, soins de support)

Menée auprès de 344 oncologues, cette étude américaine analyse leurs connaissances relatives aux solutions de préservation de la fertilité pour les jeunes patientes atteintes de cancer

• Oncologists’ Confidence in Knowledge of Fertility Issues for Young Women with Cancer
  • Journal of Cancer Education, pp. 1-8, 2012 (résumé)
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  Menée auprès de 344 oncologues, cette étude américaine analyse leurs connaissances relatives aux solutions de préservation de la fertilité pour les jeunes patientes atteintes de cancer

  “Oncologists’ Confidence in Knowledge of Fertility Issues for Young Women with Cancer”

  • Duffy, Christine;Allen, Susan;Dube, Catherine;Dickersin, Kay

  We sought to identify factors associated with greater cancer-related fertility knowledge in a national survey of oncologists. We surveyed 344 oncologists from a sampling pool drawn randomly from the AMA Masterfile. We conducted multiple linear regression to determine the relationship between confidence in knowledge and oncologists’ characteristics. Respondents’ average age was 48.5, and 75.3% were male. The average confidence in knowledge summary score was 23.8 (SD 6.4, range 8–40). In multivariable regression, confidence was higher among oncologists with more information resources, a sense of responsibility to discuss fertility issues and among gynecologic oncologists vs. other oncology specialties. Physician age, gender, and practice setting were not associated with fertility-related knowledge. Oncologists lack confidence in their knowledge of fertility issues in young women with breast cancer. Increasing professional responsibility to discuss fertility and greater information ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Qualité de vie, soins de support)

A partir des données de l'étude transversale "National Health and Nutrition Examination Survey" incluant 5 579 participants âgés de 14 à 69 ans, cette étude analyse la prévalence des infections de la cavité buccale par le papillomavirus humain aux Etats-Unis sur la période 2009-2010

• Prevalence of Oral HPV Infection in the United States, 2009-2010
  • JAMA: The Journal of the American Medical Association, sous presse, 2012 (résumé)
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  A partir des données de l'étude transversale "National Health and Nutrition Examination Survey" incluant 5 579 participants âgés de 14 à 69 ans, cette étude analyse la prévalence des infections de la cavité buccale par le papillomavirus humain aux Etats-Unis sur la période 2009-2010

  “Prevalence of Oral HPV Infection in the United States, 2009-2010”

  • Gillison, Maura L.;Broutian, Tatevik;Pickard, Robert K. L.;Tong, Zhen-you;Xiao, Weihong;Kahle, Lisa;Graubard, Barry I.;Chaturvedi, Anil K.

  Context Human papillomavirus (HPV) infection is the principal cause of a distinct form of oropharyngeal squamous cell carcinoma that is increasing in incidence among men in the United States. However, little is known about the epidemiology of oral HPV infection.Objective To determine the prevalence of oral HPV infection in the United States.Design, Setting, and Participants A cross-sectional study was conducted as part of the National Health and Nutrition Examination Survey (NHANES) 2009-2010, a statistically representative sample of the civilian noninstitutionalized US population. Men and women aged 14 to 69 years examined at mobile examination centers were eligible. Participants (N = 5579) provided a 30-second oral rinse and gargle with mouthwash. For detection of HPV types, DNA purified from oral exfoliated cells was evaluated by polymerase chain reaction and type-specific hybridization. Demographic and behavioral data were obtained by standardized interview. Statistical analyses ...

  
  

Mots clés : Voies aérodigestives supérieures; Lutte contre les cancers (Observation)

Menée aux Pays-Bas, cette étude analyse la prévalence et l'incidence du cancer du sein chez des femmes âgées de plus de 75 ans et qui ne sont plus invitées au dépistage

• Breast cancer among women over 75 years: an important public health problem?
  • The European Journal of Public Health, sous presse, 2012 (résumé)
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  Menée aux Pays-Bas, cette étude analyse la prévalence et l'incidence du cancer du sein chez des femmes âgées de plus de 75 ans et qui ne sont plus invitées au dépistage

  “Breast cancer among women over 75 years: an important public health problem?”

  • van Schoor, Guido;Otten, Johannes D.M.;den Heeten, Gerard J.;Holland, Roland;Broeders, Mireille J.M.;Verbeek, André L.M.

  Women aged >75 years are not invited for mammographic screening; if diagnosed with breast cancer, due to their anticipated short-life expectancy, they are expected to die of other causes. To describe the breast cancer health problem in women aged >75 years, we estimated breast cancer incidence in this age group and the risk of breast cancer death in patients diagnosed after 75 years of age in Nijmegen, the Netherlands. Our findings demonstrate that in this age group, 3.3% of the women will be diagnosed with breast cancer, and that one in three of these incident cases die of this disease. These patients could have benefited from continued screening.

  
  

Mots clés : Sein; Lutte contre les cancers (Observation)

A partir d'une revue de la littérature (14 études), cette étude analyse les relations entre des facteurs psychosociaux (détresse émotionnelle, satisfaction vis-à-vis de l'information médicale, spiritualité, aide et soutien social, etc.) et la qualité de vie de patients atteints de cancers hématologiques

• Are psychosocial factors associated with quality of life in patients with haematological cancer? A critical review of the literature
  • Psycho-Oncology, sous presse, 2012 (résumé)
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  A partir d'une revue de la littérature (14 études), cette étude analyse les relations entre des facteurs psychosociaux (détresse émotionnelle, satisfaction vis-à-vis de l'information médicale, spiritualité, aide et soutien social, etc.) et la qualité de vie de patients atteints de cancers hématologiques

  “Are psychosocial factors associated with quality of life in patients with haematological cancer? A critical review of the literature”

  • Allart, Priscilla;Soubeyran, Pierre;Cousson-Gélie, Florence

  Background Haematological cancers differ from other cancers mainly with regard to treatment strategies: surgery is used for diagnostic purposes but rarely for treatment, whereas chemotherapy is of central importance and, in some cases, cures patients. This article reviews studies that examine the relationships between psychosocial factors and quality of life (QoL) in haematological cancer patients. Methods A review of the literature was conducted from the databases ‘PsycInfo’, ‘Medline’ and ‘Science Direct’ using the keywords ‘lymphoma’, ‘leukaemia’, ‘myeloma’, ‘quality of life’, ‘psychosocial factors’, ‘coping’, ‘social support’, ‘personality’, ‘anxiety,’ ‘depression’, ‘locus of control’ and ‘alexithymia’. Results Fourteen studies were analysed. One study found positive relationships between sense of coherence and health-related QoL, whereas another showed a positive link between self-esteem and QoL. Another study suggested ...

  
  

Mots clés : Sang (autre); Lutte contre les cancers (Approches psycho-sociales)

Menée au Japon auprès de 8 000 participants, cette étude transversale analyse et compare, pour des patients atteints de cancer et pour une population générale non malade, les préférences relatives au lieu de soins et au lieu de fin de vie

• Preferred place of care and place of death of the general public and cancer patients in Japan
  • Supportive Care in Cancer, pp. 1-8, 2012 (résumé)
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  Menée au Japon auprès de 8 000 participants, cette étude transversale analyse et compare, pour des patients atteints de cancer et pour une population générale non malade, les préférences relatives au lieu de soins et au lieu de fin de vie

  “Preferred place of care and place of death of the general public and cancer patients in Japan”

  • Yamagishi, Akemi;Morita, Tatsuya;Miyashita, Mitsunori;Yoshida, Saran;Akizuki, Nobuya;Shirahige, Yutaka;Akiyama, Miki;Eguchi, Kenji

  Dying at a favorite place is one of the important determinants for terminally ill cancer patients. The primary aim was to clarify (1) differences in preferred place of care and place of death among the general public across four areas across Japan and (2) preferred place of care and place of death among community-representative cancer patients. A cross-sectional mail survey was conducted on 8,000 randomly selected general population. We examined preferred place of care and place of death using two vignettes and obtained a total of 3,984 (50%) responses. For the pain scenario, approximately 50% of the general public throughout four areas chose home as their preferred place of care; and for the dependent-without-pain scenario, about 40% chose home as preferred place of care. In cancer patients, for both scenarios, approximately 40% chose home as the preferred place of care, and they were significantly less likely to choose home. The most preferred combination of place of care and place ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Approches psycho-sociales)

Menée auprès de 501 membres de la famille de patients atteints d'un cancer en phase terminale, cette étude coréenne analyse les conséquences positives de leur rôle d'aidant auprès du malade

• Factors associated with positive consequences of serving as a family caregiver for a terminal cancer patient
  • Psycho-Oncology, sous presse, 2012 (résumé)
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  Menée auprès de 501 membres de la famille de patients atteints d'un cancer en phase terminale, cette étude coréenne analyse les conséquences positives de leur rôle d'aidant auprès du malade

  “Factors associated with positive consequences of serving as a family caregiver for a terminal cancer patient”

  • Kang, Jina;Shin, Dong Wook;Choi, Ji Eun;Sanjo, Makiko;Yoon, Soo Jin;Kim, Hwan Kyun;Oh, Myoung Suk;Kwen, Hyang Suk;Choi, Hae Young;Yoon, Wook Hee

  Background We examined factors associated with positive consequences for family members who served as caregivers of terminal cancer patients. Methods We conducted a nationwide cross-sectional survey of 501 bereaved family members who served as caregivers for terminal cancer patients. The main outcomes were measured by the previously developed Caregiving Consequences Inventory, which assesses perceived rewards and burdens of caregiving. Results Bereaved family caregivers reported high levels of perceived rewards and burden. Among the characteristics of bereaved family members, older age, female gender, and having a religion were associated with some domains of perceived rewards, but being a spouse of a patient was negatively associated with some domains of perceived rewards. Caregiver depression or perceived burden did not affect positive consequences of caregiving. However, receiving bereavement care was significantly associated with positive outcome in all four perceived reward ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Approches psycho-sociales)

Menée aux Etats-Unis auprès de 100 survivants adolescents d'un cancer pédiatrique, qu'il s'agisse d'une tumeur cérébrale ou d'une leucémie lymphoblastique aiguë, cette étude analyse leurs besoins en termes de suivi psychologique

• Are the psychological needs of adolescent survivors of pediatric cancer adequately identified and treated?
  • Psycho-Oncology, sous presse, 2012 (résumé)
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  Menée aux Etats-Unis auprès de 100 survivants adolescents d'un cancer pédiatrique, qu'il s'agisse d'une tumeur cérébrale ou d'une leucémie lymphoblastique aiguë, cette étude analyse leurs besoins en termes de suivi psychologique

  “Are the psychological needs of adolescent survivors of pediatric cancer adequately identified and treated?”

  • Kahalley, Lisa S.;Wilson, Stephanie J.;Tyc, Vida L.;Conklin, Heather M.;Hudson, Melissa M.;Wu, Shengjie;Xiong, Xiaoping;Stancel, Heather H.;Hinds, Pamela S.

  Objectives To describe the psychological needs of adolescent survivors of acute lymphoblastic leukemia (ALL) or brain tumor (BT), we examined the following: (i) the occurrence of cognitive, behavioral, and emotional concerns identified during a comprehensive psychological evaluation and (ii) the frequency of referrals for psychological follow-up services to address identified concerns. Methods Psychological concerns were identified on measures according to predetermined criteria for 100 adolescent survivors. Referrals for psychological follow-up services were made for concerns previously unidentified in formal assessment or not adequately addressed by current services. Results Most survivors (82%) exhibited at least one concern across domains: behavioral (76%), cognitive (47%), and emotional (19%). Behavioral concerns emerged most often on scales associated with executive dysfunction, inattention, learning, and peer difficulties. Cranial radiation therapy was associated with cognitive ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Approches psycho-sociales)

A partir de l'étude d'un cas, cet article analyse le stress, les difficultés psychologiques et psychosomatiques rencontrées par les proches et membres de la famille soignant des adultes atteints de cancer

• Caregiving Burden, Stress, and Health Effects Among Family Caregivers of Adult Cancer Patients
  • JAMA: The Journal of the American Medical Association, Vol. 307 (4), pp. 398-403, 2012 (résumé)
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  A partir de l'étude d'un cas, cet article analyse le stress, les difficultés psychologiques et psychosomatiques rencontrées par les proches et membres de la famille soignant des adultes atteints de cancer

  “Caregiving Burden, Stress, and Health Effects Among Family Caregivers of Adult Cancer Patients”

  • Bevans, Margaret;Sternberg, Esther M.

  Unlike professional caregivers such as physicians and nurses, informal caregivers, typically family members or friends, provide care to individuals with a variety of conditions including advanced age, dementia, and cancer. This experience is commonly perceived as a chronic stressor, and caregivers often experience negative psychological, behavioral, and physiological effects on their daily lives and health. In this report, we describe the experience of a 53-year-old woman who is the sole caregiver for her husband, who has acute myelogenous leukemia and was undergoing allogeneic hematopoietic stem cell transplantation. During his intense and unpredictable course, the caregiver's burden is complex and complicated by multiple competing priorities. Because caregivers are often faced with multiple concurrent stressful events and extended, unrelenting stress, they may experience negative health effects, mediated in part by immune and autonomic dysregulation. Physicians and their ...

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Approches psycho-sociales)

Menée en Turquie auprès de 154 étudiants en 3ème année de médecine, cette étude évalue l'intérêt et l'efficacité d'un module de formation axé autour de la communication entre soignants et patients atteints de cancer

• Effects and Permanency of the Training Program “Communication with Cancer Patients” on the Opinions of Students
  • Journal of Cancer Education, pp. 1-4, 2012 (résumé)
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  Menée en Turquie auprès de 154 étudiants en 3ème année de médecine, cette étude évalue l'intérêt et l'efficacité d'un module de formation axé autour de la communication entre soignants et patients atteints de cancer

  “Effects and Permanency of the Training Program “Communication with Cancer Patients” on the Opinions of Students”

  • Senol, Yesim;Ozdogan, Mustafa;Bozcuk, Hakan

  Learning to develop the doctor–patient relationship is very important in the treatment of patients with cancer. We aim to train our students in the early years of study about this subject with a course on the patient–doctor communication, prepared for third year students. One hundred fifty-four third year students participated in our study during the 2006–2007 academic years. The same questionnaire was given to the students in the 2009–2010 academic year; their sixth year of study. The rate of return for the questionnaire is 88.7%. Based on this study, we have the opinion that the training given in the third year is beneficial; however, the efficacy of the training diminishes with the advancing years, and therefore, the length of this training should be increased in the upper classes and additional hours should be added.

  
  

Mots clés : Cancer (général); Lutte contre les cancers (Sensibilisation et communication)